Covid-19: Reports from Israel suggest one dose of Pfizer vaccine could be less effective than expected

نویسندگان

چکیده

In a recent study on Gulf War veterans who developed delayed neurotoxicity symptoms, we found their levels of serum paraoxonase (PON1) isozyme type Q to be significantly lower than in the control, unaffected veteran group. These results were obtained 25 ill and 20 well control subjects, which 10 deployed nondeployed battalion members remained United States during War. The blood samples also assayed for butyrylcholinesterase our laboratory, more recently Dr. C. Broomfield9s laboratory somanase sarinase activities. cholinesterase activities showed no significant correlation with PON1 or severity clinical but ran parallel concentrations. Although there is direct evidence that these directly exposed encountered either nerve gases, they may have been some environmental chemical toxin similar preference hydrolysis by isozyme. number subjects relatively small, should encourage other investigators examine both individual phenotypes isozymes groups exhibiting neurological symptoms.

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ژورنال

عنوان ژورنال: BMJ

سال: 2021

ISSN: ['0959-8138']

DOI: https://doi.org/10.1136/bmj.n217